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Invitrogen
ABI2 Recombinant Rabbit Monoclonal Antibody (JE53-89)
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ABI2 Antibody (MA5-36165) in IHC (P)
Immunohistochemical analysis of ABI2 in paraffin-embedded mouse testis tissue using a monoclonal antibody (Product #MA5-36165). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (1:50) for 30 minutes at... View More
产品信息
MA5-36165
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JE53-89
抗原
Recombinant protein within Human ABI2 aa 312-411
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Abelson interactor 2; Abi-2; abl binding protein 3; Abl interactor 2; Abl-binding protein 3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AblBP3; arg protein tyrosine kinase-binding protein; Arg-binding protein 1; ArgBP1
基因别名: 8430425M24Rik; ABI-2; ABI2; ABI2B; AblBP3; AI839867; AIP-1; argBP1; ARGBPIA; argBPIB; C130078H13; SSH3BP2
UniProt ID: (Human) Q9NYB9, (Mouse) P62484
Entrez Gene ID: (Human) 10152, (Mouse) 329165
movement of cell or subcellular component
cytoskeleton organization
actin polymerization or depolymerization
viral process
cell migration
Rac protein signal transduction
peptidyl-tyrosine phosphorylation
positive regulation of Arp2/3 complex-mediated actin nucleation
learning or memory
dendrite development
camera-type eye development
