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Bethyl Laboratories
ACC1/ACC-alpha Polyclonal Antibody
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ACC1/ACC-alpha Antibody (A300-986A) in IP
Detection of human ACC1/ACC-alpha by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-ACC1/ACC-alpha antibody (Product # A300-986A) used for IP at 3 µg/mg lysate. ACC1/ACC-alpha was blotted using rabbit anti-ACC1/ACC-alpha antibody A300-987A, which recognizes a downstream epitope. For blotting immunoprec... View More
产品信息
A300-986A
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1925 and 1975 of human acetyl-Coenzyme A carboxylase alpha.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
靶标信息
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ACAC; ACAC1; ACACA; ACACAD; ACACalpha; acc; Acc-1; ACC-alpha; ACC1; ACC2; accA; ACCalpha; ACCase; accB; accC; accD; Acetyl-CoA carboxylase 1; Acetyl-Coenzyme A carboxylase alpha; alpha-CT; BC; BCCP; beta-CT; biotin carboxyl carrier protein; biotin carboxylase; carboxyltransferase subunit alpha; carboxyltransferase subunit beta; EC 6.3.4.14; EC 6.4.1.2; hACC1; unnamed protein product
基因别名: ACAC; Acac1; ACACA; ACACAD; ACACalpha; ACC; ACC1; ACCA; ACCalpha; hACC1
UniProt ID: (Human) Q13085
Entrez Gene ID: (Human) 31
tissue homeostasis
acetyl-CoA metabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
acyl-CoA metabolic process
lipid biosynthetic process
fatty-acyl-CoA biosynthetic process
protein homotetramerization
lipid homeostasis
cellular response to prostaglandin E stimulus
malonyl-CoA biosynthetic process
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