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Abnova
ACCN3 Polyclonal Antibody, MaxPab™
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产品信息
H00009311-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ACCN3 (NP_064717.1, 1 a.a. approximately 549 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKPTSGPEEA RRPASDIRVF ASNCSMHGLG HVFGPGSLSL RRGMWAAAVV LSVATFLYQV AERVRYYREF HHQTALDERE SHRLIFPAVT LCNINPLRRS RLTPNDLHWA GSALLGLDPA EHAAFLRALG RPPAPPGFMP SPTFDMAQLY ARAGHSLDDM LLDCRFRGQP CGPENFTTIF TRMGKCYTFN SGADGAELLT TTRGGMGNGL DIMLDVQQEE YLPVWRDNEE TPFEVGIRVQ IHSQEEPPII DQLGLGVSPG YQTFVSCQQQ QLSFLPPPWG DCSSASLNPN YEPEPSDPLG SPSPSPSPPY TLMGCRLACE TRYVARKCGC RMVYMPGDVP VCSPQQYKNC AHPAIDAMLR KDSCACPNPC ASTRYAKELS MVRIPSRAAA RFLARKLNRS EAYIAENVLA LDIFFEALNY ETVEQKKAYE MSELLGDIGG QMGLFIGASL LTILEILDYL CEVFRDKVLG YFWNRQHSQR HSSTNLLQEG LGSHRTQVPH LSLGPSTLLC SEDLPPLPVP SPRLSPPPTA PATLSHSSRP AVCVLGAPP
靶标信息
ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acid sensing (proton gated) ion channel 3; acid sensing ion channel 3; acid-sensing (proton-gated) ion channel 3; Acid-sensing ion channel 3; Amiloride-sensitive cation channel 3; amiloride-sensitive cation channel 3, testis; ASIC3; hASIC3; hTNaC1; modulatory subunit of ASIC2a; Neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; Testis sodium channel 1
基因别名: ACCN3; ASIC3; DRASIC; SLNAC1; TNAC1
UniProt ID: (Human) Q9UHC3
Entrez Gene ID: (Human) 9311
transport
signal transduction
sensory perception
response to heat
response to acidic pH
ion transmembrane transport
sodium ion transmembrane transport
enterobactin transport
sensory perception of sour taste
detection of temperature stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of pain
detection of chemical stimulus involved in sensory perception of pain
