Search
Agrisera
ACD1/Accelerated cell death 1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
ACD1/Accelerated cell death 1 Antibody (AS11-1783) in WB
Arabidopsis thaliana wild ecotype Columbia was grown for four weeks under continuous illumination and then transferred to complete darkness for five days. Several leaves were harvested from the plants before they were transferred to darkness (0 d) or after they were kept for five days (5 d). Protein was extracted with the SDS extraction solution containing 50 m M Tris (p H 6.8), 10% (w/v) glycerol, 2% (w/v)... View More
产品信息
AS11-1783
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
Recombinant PaO from Arabidopsis thaliana.
偶联物
形式
Lyophilized
保存液
whole serum
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
ACD1 encodes a chloroplast-associated enzyme of the chlorophyll catabolic pathway that localizes to plastids (consistent with a chloroplast transit peptide) and functions during leaf senescence and stress-related chlorophyll breakdown. The ACD1 protein is a Rieske-type oxygenase/monooxygenase of the pheophorbide a oxygenase (PaO) step, containing a Rieske 2Fe-2S cluster-binding module and a non-heme iron catalytic center typical of aromatic-ring-hydroxylating dioxygenase-like enzymes, enabling oxygenolytic opening of the pheophorbide a tetrapyrrole macrocycle. Biologically, ACD1 activity is required to convert pheophorbide a into downstream chlorophyll catabolites; when ACD1/PaO activity is reduced (e.g., by antisense suppression), pheophorbide a accumulates and triggers cellular damage and accelerated cell death, including photooxidative injury upon re-illumination after dark-induced senescence, demonstrating that controlled PaO function is essential both for efficient chlorophyll detoxification during senescence and for limiting pro-death signaling/toxicity from chlorophyll catabolic intermediates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ACCELERATED CELL DEATH 1; AT3G44880; LETHAL LEAF-SPOT 1 HOMOLOG; LLS1; PAO; PHEOPHORBIDE A OXYGENASE
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
