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Invitrogen
ACOX1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-82751
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AVRHQSEIKP GEPEPQILDF QTQQYKLFPL LATAYAFQFV GAYMKETYHR INEGIGQGDL SELPELHALT AGLKAFTSWT ANTGIEACRM ACGGHGY
Highest antigen sequence indentity to the following orthologs: Mouse - 88%, Rat - 90%.
靶标信息
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acyl-CoA oxidase 1, palmitoyl; acyl-CoA oxidase, straight-chain; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; palmitoyl-CoA oxidase; peroxisomal fatty acyl-CoA oxidase; straight-chain acyl-CoA oxidase; unnamed protein product
基因别名: ACOX; AOX; MITCH; PALMCOX; SCOX
UniProt ID: (Human) Q15067
Entrez Gene ID: (Human) 51
acyl-CoA oxidase activity
fatty acid binding
protein binding
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
PDZ domain binding
protein homodimerization activity
very-long-chain fatty acyl-CoA oxidase activity
flavin adenine dinucleotide binding
FAD binding
medium-chain fatty acyl-CoA oxidase activity
long-chain fatty acyl-CoA oxidase activity
very long-chain fatty acid metabolic process
generation of precursor metabolites and energy
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
prostaglandin metabolic process
fatty acid catabolic process
peroxisome fission
fatty acid oxidation
fatty acid beta-oxidation using acyl-CoA oxidase
cholesterol homeostasis
hydrogen peroxide biosynthetic process
lipid homeostasis
very long-chain fatty acid beta-oxidation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
