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Invitrogen
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This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acetyl-Coenzyme A synthetase 2 (ADP forming); acetyl-coenzyme A synthetase, cytoplasmic
基因别名: Acas2
Entrez Gene ID: (Rat) 311569