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Bethyl Laboratories
ACTR2/ARP2 Polyclonal Antibody
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ACTR2/ARP2 Antibody (A305-217A) in IHC (P)
Detection of human ACTR2 by immunohistochemistry. Sample: FFPE section of human skin squamous cell carcinoma. Antibody: Affinity purified rabbit anti-ACTR2 (Product # A305-217A) (Lot 1) used at a dilution of 1:5,000 (0.2 µg/mL). Detection: DAB. Counterstain: IHC Hematoxylin (blue).
产品信息
A305-217A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 250 to 300 of human Actin-related protein 2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken, Bovine and Orangutan
靶标信息
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Actin-like protein 2; Actin-related protein 2; ARP2 actin-related protein 2 homolog
基因别名: ACTR2; ARP2
UniProt ID: (Human) P61160
Entrez Gene ID: (Human) 10097
movement of cell or subcellular component
establishment or maintenance of cell polarity
asymmetric cell division
meiotic chromosome movement towards spindle pole
cytosolic transport
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
Fc-gamma receptor signaling pathway involved in phagocytosis
cilium assembly
ephrin receptor signaling pathway
spindle localization
