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Invitrogen
ADAM19 Polyclonal Antibody
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ADAM19 Antibody (PA5-116510) in WB
Western blot analysis of ADAM19 in extracts of various cell lines. Samples were incubated with ADAM19 Polyclonal antibody (Product # PA5-116510) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-116510
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 203-460 of human ADAM19 (NP_1503771)
偶联物
形式
Liquid
浓度
0.56 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HT-1080, SW480, NIH/3T3, Mouse heart, Mouse lung, Mouse liver, Mouse kidney, Rat heart
Immunogen sequence: REDLNSMKYV ELYLVADYLE FQKNRRDQDA TKHKLIEIAN YVDKFYRSLN IRIALVGLEV WTHGNMCEVS ENPYSTLWSF LSWRRKLLAQ KYHDNAQLIT GMSFHGTTIG LAPLMAMCSV YQSGGVNMDH SENAIGVAAT MAHEMGHNFG MTHDSADCCS ASAADGGCIM AAATGHPFPK VFNGCNRREL DRYLQSGGGM CLSNMPDTRM LYGGRRCGNG YLEDGEECDC GEEEECNNPC CNASNCTLRP GAECAHGS
靶标信息
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: a disintegrin and metallopeptidase domain 19 (meltrin beta); a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 19 (meltrin beta); ADAM; ADAM 19; ADAMs; Disintegrin and metalloproteinase domain-containing protein 19; MADDAM; meltrin beta; Meltrin-beta; metalloendopeptidases; Metalloprotease and disintegrin dendritic antigen marker; metalloprotease-disintegrin meltrin beta; SRY-box containing gene 30
基因别名: ADAM19; AL024287; FKSG34; MADDAM; MLTNB; Sox30
UniProt ID: (Human) Q9H013, (Mouse) O35674
Entrez Gene ID: (Human) 8728, (Rat) 303068, (Mouse) 11492
