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Invitrogen
ADAM9 Recombinant Rabbit Monoclonal Antibody (2A0V9)
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ADAM9 Antibody (MA5-58018) in WB
Western blot analysis of ADAM9 in A-431 and Hep G2 (25 µg/lane). Samples were incubated overnight at 4°C with ADAM9 Recombinant Monoclonal Antibody (Product # MA5-58018) using a dilution of 1:13, 000. Followed by a HRP-conjugated Goat anti-Rabbit IgG (H+L) Secondary Antibody at 1:10,000 dilution. Blocking buffer: 3% nonfat dry milk in TBST; Exposure: 30 seconds.
产品信息
MA5-58018
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2A0V9
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 29-210 of human ADAM9 (NP_003807.1).
偶联物
形式
Liquid
浓度
2.51 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
产品详细信息
Immunogen sequence: AARPGFQQTS HLSSYEIITP WRLTRERREA PRPYSKQVSY VIQAEGKEHI IHLERNKDLL PEDFVVYTYN KEGTLITDHP NIQNHCHYRG YVEGVHNSSI ALSDCFGLRG LLHLENASYG IEPLQNSSHF EHIIYRMDDV YKEPLKCGVS NKDIEKETAK DEEEEPPSMT QLLRRRRAVL PQ
靶标信息
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: a disintegrin and metalloproteinase; ADAM; ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); ADAMs; Cellular disintegrin-related protein; cone rod dystrophy 9; Disintegrin and metalloproteinase domain-containing protein 9; MDC 9; Meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485
基因别名: ADAM9; CORD9; KIAA0021; MCMP; MDC9; MLTNG
UniProt ID: (Human) Q13443
Entrez Gene ID: (Human) 8754
activation of MAPKK activity
membrane protein ectodomain proteolysis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
response to manganese ion
cell migration
keratinocyte differentiation
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
cell-cell adhesion mediated by integrin
positive regulation of macrophage fusion
response to tumor necrosis factor
monocyte activation
response to hydrogen peroxide
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
PMA-inducible membrane protein ectodomain proteolysis
response to glucocorticoid
positive regulation of keratinocyte migration
response to calcium ion
cellular response to lipopolysaccharide
