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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects endogenous levels of total ADAMTS6 protein.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloproteinase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6; a-disintegrin-and-metalloprotease with thrombospondin type 1 motif 6; ADAM; ADAMs; metalloendopeptidases; unnamed protein product
Gene Aliases: ADAM-TS 6; ADAM-TS6; ADAMTS-6
UniProt ID: (Human) Q9UKP5
Entrez Gene ID: (Human) 11174
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