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Invitrogen
ADORA2B Polyclonal Antibody
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ADORA2B Antibody (PA5-103182) in ICC/IF
Immunofluorescent analysis of ADORA2B in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and ADORA2B polyclonal antibody (Product # PA5-103182) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-103182
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ADORA2B(Accession P29275), corresponding to amino acid residues T118-L168.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ADORA2B.
靶标信息
ADORA2B encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A2b receptor; Adenosine receptor A2b; HGNC:264; netrin-1 receptor
基因别名: ADORA2; ADORA2B
UniProt ID: (Rat) P29276
Entrez Gene ID: (Human) 136, (Rat) 29316
adenosine receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
vasodilation
presynaptic modulation of chemical synaptic transmission
positive regulation of chronic inflammatory response to non-antigenic stimulus
positive regulation of cell proliferation
negative regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of norepinephrine secretion
positive regulation of steroid biosynthetic process
positive regulation of cAMP biosynthetic process
positive regulation of cGMP biosynthetic process
positive regulation of guanylate cyclase activity
cellular response to extracellular stimulus
positive regulation of chemokine production
positive regulation of interleukin-6 production
negative regulation of collagen biosynthetic process
positive regulation of catecholamine secretion
positive regulation of mast cell degranulation
regulation of angiogenesis
positive regulation of vasodilation
relaxation of vascular smooth muscle
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