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This antibody detects endogenous protein at a molecular weight of 38 kDa.
Purity is >95% by SDS-PAGE.
Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNF alpha and blocks the endotoxin CD14 receptor signal transduction pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AD026; Adenosine A3-R; Adenosine receptor A3; BA552M11.5; G-protein coupled receptor 2; RP11-552M11.7
基因别名: A3AR; A3R; AA3R; ADORA3; ARA3; Gpcr2; Tgpcr1
UniProt ID: (Human) P0DMS8
Entrez Gene ID: (Human) 140, (Mouse) 11542, (Rat) 25370
分子生物学功能: G-protein coupled receptor