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Invitrogen
AHI1-DT Recombinant Mouse Monoclonal Antibody (K92101_8E8)
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AHI1-DT Antibody (MA568004) in IHC (P)
Immunohistochemical (Paraffin) analysis of AHI1-DT in lymph node tissue using AHI1-DT Recombinant Monoclonal Antibody (Product # MA568004). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% Hydrogen Peroxide for 30 min at room temperature. The sections were then incubated with... View More
产品信息
MA568004
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K92101_8E8
抗原
Recombinant human AHI1-DT.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
AHI1 DT is annotated as a divergent or downstream transcript associated with the AHI1 locus, which encodes Abelson helper integration site protein 1, a scaffold involved in ciliary function and neurodevelopment. AHI1 DT is a noncoding RNA transcript lacking a clear protein coding open reading frame, and like many locus associated noncoding RNAs it may regulate nearby gene expression through chromatin interaction, transcriptional interference, or RNA mediated scaffolding of regulatory complexes. Expression of AHI1 DT appears tissue specific with signals in brain related datasets, consistent with the neurodevelopmental relevance of AHI1, but detailed functional characterization remains limited. Potential roles include modulation of ciliogenesis pathways, neuronal differentiation, or stress responses, inferred from coexpression and genomic proximity rather than direct mechanistic data. Experimental approaches to study AHI1 DT typically include RNA sequencing, quantitative PCR, CRISPR interference or antisense knockdown to perturb transcription, RNA binding protein pulldown to identify interactors, and chromatin assays to assess local regulatory effects. Overall, AHI1 DT is best considered a candidate regulatory noncoding RNA linked to the AHI1 genomic region, with active research needed to define its molecular functions and clinical significance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AHI1 divergent transcript
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