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Invitrogen
AHRR Polyclonal Antibody
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AHRR Antibody (PA5-50626) in WB
Western Blot analysis of AHRR was performed using (left to right): Mouse liver tissue lysates and HepG2 cells. The membrane was probed using AHRR Polyclonal Antibody (Product # PA5-50626) 1:430 dilution. Secondary antibody dilution: 1:8,000. Exposure time: 2 minutes.
产品信息
PA5-50626
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues near the N terminal of human aryl-hydrocarbon receptor repressor
偶联物
形式
Liquid
浓度
1.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total AHRR protein.
靶标信息
The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AhR repressor; aryl hydrocarbon hydroxylase regulator; Aryl hydrocarbon receptor repressor; bHLHe77; Class E basic helix-loop-helix protein 77; dioxin receptor repressor
基因别名: AHH; AHHR; AHRR; BHLHE77; KIAA1234; mKIAA1234
UniProt ID: (Human) A9YTQ3, (Mouse) Q3U1U7
Entrez Gene ID: (Human) 57491, (Mouse) 11624
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
response to xenobiotic stimulus
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
xenobiotic metabolic process
signal transduction
positive regulation of protein sumoylation
negative regulation of transcription, DNA-templated
