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Invitrogen
AIM2 Polyclonal Antibody
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产品信息
PA5-91996
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide
偶联物
形式
Liquid
浓度
1.28 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: HeLa, HepG2; Cellular Location: Cytoplasm, Nucleus
Immunogen sequence: HVKPEQKQMV AQQESIREGF QKRCLPVMVL KAKKPFTFET QEGKQEMFHA TVATEKEFFF VKVFNTLLKD KFIPKRIIII ARYYRHSGFL EVNSASRVLD AESDQKVNVP LNIIRKAGET PKINTLQTQP LGTIVNGLFV VQKVTEKKKN ILFDLSDNTG KMEVLGVRNE DTMKCKEGDK VRLTFFTLSK NGEKLQLTSG VHSTIKVI
靶标信息
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Absent in melanoma 2; Ifi-210; Interferon-inducible protein 210; Interferon-inducible protein AIM2; Interferon-inducible protein p210; RP11-520H16.3
基因别名: AIM2; Gm1313; Ifi210; PYHIN4
UniProt ID: (Human) O14862, (Mouse) Q91VJ1
Entrez Gene ID: (Human) 9447, (Rat) 304987, (Mouse) 383619
activation of innate immune response
positive regulation of defense response to virus by host
apoptotic process
inflammatory response
immune response
negative regulation of NF-kappaB transcription factor activity
positive regulation of protein oligomerization
positive regulation of interleukin-1 beta production
tumor necrosis factor-mediated signaling pathway
cellular response to interferon-beta
cellular response to drug
innate immune response
interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
positive regulation of NF-kappaB transcription factor activity
pyroptosis
positive regulation of cysteine-type endopeptidase activity
biological_process
immune system process
