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AK1 Antibody (H00000203-D01P) in WB
Western Blot analysis of AK1 expression in transfected 293T cell line (H00000203-T01) by AK1 MaxPab polyclonal antibody.
Lane 1: AK1 transfected lysate(21.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: AK1 transfected lysate(21.60 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00000203-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
AK1 (NP_000467.1, 1 a.a. approximately 194 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MEEKLKKTKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD SVFSQVCTHL DALK
靶标信息
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenylate kinase isoenzyme 1; Adenylate monophosphate kinase; AK 1; ATP-AMP transphosphorylase 1; ATP:AMP phosphotransferase; cytosolic adenylate kinase; Myokinase; testis secretory sperm binding protein Li 58j
基因别名: Ak-1; AK1; B430205N08Rik; HTL-S-58j
UniProt ID: (Human) P00568, (Mouse) Q9R0Y5
Entrez Gene ID: (Human) 203, (Mouse) 11636
nucleoside diphosphate phosphorylation
ADP biosynthetic process
cell cycle arrest
nucleoside triphosphate biosynthetic process
nucleobase-containing small molecule interconversion
AMP metabolic process
ATP metabolic process
nucleobase-containing compound metabolic process
positive regulation of glucose transport
phosphorylation
inosine biosynthetic process
nucleotide phosphorylation
