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Invitrogen
ALAS2 Recombinant Rabbit Monoclonal Antibody (24GB6795)
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图: 1 / 3
ALAS2 Antibody (MA5-56959) in ICC/IF
Immunocytochemistry analysis of ALAS2 in HepG2 cells. Sample was incubated with ALAS2 monoclonal (Product # MA5-56959) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: High. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-56959
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB6795
抗原
A synthesized peptide derived from human ALAS2 (aa 568-580)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.6 mg/mL
规格
60 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-aminolevulinic acid synthase (EC 2.3.1.37); 5-aminolevulinic acid synthase 2; ALAS-E; Aminolevulinate synthase 2, delta; aminolevulinate, delta-, synthase 2; aminolevulinic acid synthase 2, erythroid; aminolevulinic acid synthase 2, erythroid-like; delta-ALA synthase 2; delta-ALA synthetase; delta-aminolevulinate synthase 2; erythroid-specific ALAS; erythroid-specific delta-aminolevulinate synthase; erythroid-specific delta-aminolevulinate synthase ALAS-E; PRO2399; RP5-884M20.1; unnamed protein product
基因别名: ALAS; Alas-2; ALAS-E; ALASE; ANH1; ASB; SIDBA1; XLDPP; XLEPP; XLSA
UniProt ID: (Human) P22557, (Mouse) P08680, (Rat) Q63147
Entrez Gene ID: (Human) 212, (Mouse) 11656, (Rat) 25748
response to hypoxia
porphyrin-containing compound metabolic process
heme biosynthetic process
heme B biosynthetic process
cellular iron ion homeostasis
erythrocyte differentiation
tetrapyrrole biosynthetic process
hemoglobin biosynthetic process
lactation
response to xenobiotic stimulus
response to lead ion
response to cobalt ion
maternal process involved in female pregnancy
response to fatty acid
liver regeneration
response to benzene
oxygen homeostasis
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
