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Invitrogen
ALDH1L1 Recombinant Rabbit Monoclonal Antibody (19H14L20)
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ALDH1L1 Antibody (702573) in ICC/IF
Immunofluorescence analysis of ALDH1L1 was performed using 70% confluent log phase RT4 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with ALDH1L1 Antibody (19H14L20), ABfinity Rabbit Monoclonal (Product # 702573) at 2 µg/mL in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plu... View More
产品信息
702573
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
19H14L20
抗原
Protein corresponding to Human ALDH1L1 (aa 1-307)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Monkey, Rat, Cat and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10fTHF; 10FTHFDH; aldehyde dehydrogenase 1 family, member L1; Aldehyde dehydrogenase family 1 member L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; FBP-CI; formyltetrahydrofolate dehydrogenase; MER57B-ALDH1L1
基因别名: 10-fTHF; 10-FTHFDH; 1810048F20Rik; ALDH1L1; FDH; FTHFD; Neut2
UniProt ID: (Human) O75891, (Rat) P28037, (Mouse) Q8R0Y6
Entrez Gene ID: (Human) 10840, (Rat) 64392, (Mouse) 107747
catalytic activity
aldehyde dehydrogenase (NAD) activity
formyltetrahydrofolate dehydrogenase activity
hydroxymethyl-, formyl- and related transferase activity
aminobutyraldehyde dehydrogenase activity
4-trimethylammoniobutyraldehyde dehydrogenase activity
aldehyde dehydrogenase [NAD(P)+] activity
methyltransferase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
protein complex binding
aldehyde dehydrogenase (NADP+) activity
protein binding
oxidoreductase activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
RNA processing factor
