Search
Invitrogen
ALOX5 Recombinant Rabbit Monoclonal Antibody (5C5Z2)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 6
ALOX5 Antibody (MA5-38050) in ICC/IF
Confocal imaging (Immunocytochemistry) of ALOX5 in U-2 OS cells. Samples were incubated with ALOX5 Monoclonal antibody (Product # MA5-38050) using a dilution of 1:100 (Red). The cells were counterstained with alpha Tubulin Mouse mAb (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-38050
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5C5Z2
抗原
Synthetic peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
200 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Raji, Rat lung
Immunogen sequence: CYRWITGDVE VVLRDGRAKL ARDDQIHILK QHRRKELETR QKQYRWMEWN PGFPLSIDAK CHKDLPRDIQ FDSEKGVDFV LNYSKAMENL FINRFMHMFQ S
靶标信息
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5 - Lipoxygenase; 5-lipoxygenase; 5-LO; Arachidonate 5-lipoxygenase; lox5; Polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
基因别名: ALOX5; LOG5; LOX5A
UniProt ID: (Rat) P12527
Entrez Gene ID: (Rat) 25290
acute inflammatory response
leukotriene production involved in inflammatory response
leukotriene metabolic process
inflammatory response
response to nutrient
sensory perception of pain
arachidonic acid metabolic process
leukotriene biosynthetic process
lipoxygenase pathway
positive regulation of vasoconstriction
response to hyperoxia
oxidation-reduction process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
