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Invitrogen
AMIGO3 Polyclonal Antibody
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Product Details
PA5-44452
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human AMIGO3 (aa 1-50).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: MTWLVLLGTL LCMLRVGLGT PDSEGFPPRA LHNCPYKCIC AADLLSCTGL
Sequence homology: Guinea Pig: 79%; Human: 100%
Target Information
Amphoterin induced gene and ORF 3 (AMIGO3) is a gene located on chromosome 3p21.31, encoding a member of the AMIGO family of proteins involved in cell adhesion, axon guidance, and neuronal signaling. AMIGO3 is primarily expressed in the central nervous system, playing a crucial role in neural development and the maintenance of neural circuits. Functionally, AMIGO3 contributes to neuronal growth and synapse formation, impacting processes such as neural plasticity and signal transduction. The protein's activity facilitates interactions with other neuronal surface proteins, influencing axon pathfinding and connectivity. Aberrant expression or mutations in AMIGO3 have been linked to neurological disorders and neurodegenerative diseases, suggesting its significance in neural health and pathology. Research into AMIGO3 continues to explore its potential therapeutic applications in promoting neural repair and modulating synaptic functions, offering insights into strategies for addressing nervous system disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: adhesion molecule with Ig-like domain 3; Alivin-3; AMIGO-3; AMIGO3; amphoterin-induced gene and ORF 3; Amphoterin-induced protein 3; MGC120552
Gene Aliases: ALI3; AMIGO-3; AMIGO3; KIAA1851; UNQ6084/PRO20089
UniProt ID: (Human) Q86WK7
Entrez Gene ID: (Human) 386724
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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