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Invitrogen
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This target displays homology in the following species: Cow: 77%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 93%
AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Archaemetzincin-2; archeobacterial metalloproteinase-like 2; Archeobacterial metalloproteinase-like protein 2
基因别名: Amz2; RGD1304846
UniProt ID: (Rat) Q400C7
Entrez Gene ID: (Rat) 360650