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Invitrogen
ANGPTL4 Polyclonal Antibody
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ANGPTL4 Antibody (PA5-26216) in IHC (P)
Immunohistochemistry analysis of ANGPTL4 in formalin-fixed and paraffin-embedded human skeletal muscle. Samples were incubated with ANGPTL4 polyclonal antibody (Product # PA5-26216) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-26216
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 138-167 amino acids from the central region of human ANGPTL4
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ANGPTL2; contains fibrinogen-like domain; Fasting-i; fasting-induced adipose factor; hepatic angiopoietin-related protein; hepatic fibrinogen/angiopoietin-related protein; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PPARG angiopoietin related protein; unnamed protein product
基因别名: ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171
UniProt ID: (Human) Q9BY76
Entrez Gene ID: (Human) 51129
response to hypoxia
blood coagulation
negative regulation of very-low-density lipoprotein particle remodeling
negative regulation of apoptotic process
protein unfolding
negative regulation of fatty acid biosynthetic process
positive regulation of angiogenesis
positive regulation of multicellular organismal process
triglyceride homeostasis
regulation of chylomicron remodeling
regulation of triglyceride transport
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