Anti-ANKLE2 antibody was prepared from chicken egg fractions produced by repeated immunizations with a 19 amino acid synthetic peptide near the internal region of human ANKLE2.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: Ankyrin repeat and LEM domain-containing protein 2; LEM domain containing 7; LEM domain-containing protein 4; liver regeneration-related protein LRRG057

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基因别名: 1110001J12Rik; Ab2-034; AI661024; ANKLE2; D5Ertd585e; KIAA0692; LEM4; LEMD7; MCPH16; RGD1310191

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UniProt ID: (Human) Q86XL3, (Mouse) Q6P1H6

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Entrez Gene ID: (Human) 23141, (Mouse) 71782, (Rat) 360829

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功能

protein binding protein phosphatase type 2A regulator activity protein phosphatase 2A binding

参与通路