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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recommended positive controls: 293T, Jurkat, Raji.
Predicted reactivity: Human (99%), Mouse (84%), Rat (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: LEM domain containing 7; LEM domain-containing protein 4; LEM-domain protein 4; unnamed protein product
基因别名: KIAA0692; Lem4; LEMD7; MCPH16
UniProt ID: (Human) Q86XL3
Entrez Gene ID: (Human) 23141