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Bethyl Laboratories
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ANKRD13A, also named as ANKRD13, a 590 amino acid protein, which contains two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. ANKRD13A localizes in the cell membrane. ANKRD13A as ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin, not bind 'Lys-48'-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ankyrin repeat domain-containing protein 13A; NY-REN-25 antigen; Protein KE03
基因别名: 1100001D10Rik; ANKRD13; ANKRD13A; AU046136; NY-REN-25
UniProt ID: (Human) O60736, (Mouse) Q80UP5
Entrez Gene ID: (Human) 88455, (Mouse) 68420