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Invitrogen
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Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ankyrin repeat domain-containing protein 16
基因别名: 2810455F06Rik; AI646698; Ankrd16; D430029B21Rik
UniProt ID: (Mouse) A2AS55
Entrez Gene ID: (Mouse) 320816