Invitrogen

ANO6 Polyclonal Antibody

Name: ANO6 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-69345

高级验证

2 篇参考文献

查看其他11个ANO6抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)
高级验证 (1)

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ANO6 Antibody (PA5-69345) in WB

Western blot analysis of ANO6 on mouse liver tissue lysate. The sample was probed with a ANO6 polyclonal antibody (Product # PA5-69345) using a primary antibody dilution of 1.0 µg/mL.

Product Image Gallery

ANO6 Antibody — Knockdown of ANO6 inhibited the activation of ERK signaling. After T98G and U87MG cells transfection with ANO6-KD 1 or ANO6-KD2, (A and B) the protein expression level of ERK and phospho-ERK was detected by Western blot assay; (C) the protein expression levels of ANO6 and ERK were detected by Western blot assay in cytoplasm and cell nucleus of T98G cells; (D and E) Histograms were used to represent statistical results of the protein expression levels of ANO6 and ERK in cytoplasm and cell nucleus of T98G cells; (F) the protein expression levels of ANO6 and ERK were detected by Western blot assay in cytoplasm and cell nucleus of U87MG cells. (G and H) Histograms were used to represent statistical results of the protein expression levels of ANO6 and ERK in cytoplasm and cell nucleus of U87MG cells; β-actin was used as a load control for cytoplasm. LaminB was used as a load control for cell nucleus. Data are presented as the mean standard deviation. **p<0.05 versus ANO6-KD1 group and ANO6-KD2 group. Abbreviations: NC is negative control, Rel. is relative. {KD}

Immunogen image

Immunogen Image ANO6 Polyclonal Antibody

产品信息

PA5-69345

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1.0 µg/mL

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产品规格

种属反应

Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

synthetic peptide corresponding to a region of mouse ANO6 (aa 480-529).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2691066

产品详细信息

This target displays homology in the following species: Guinea Pig: 77%; Human: 100%; Mouse: 92%; Pig: 93%; Rat: 92%

靶标信息

May act as a calcium-activated chloride channel.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F

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基因别名: 2900059G15Rik; AA407480; Ano6; AW554778; F730003B03Rik; Tmem16f

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UniProt ID: (Mouse) Q6P9J9

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Entrez Gene ID: (Mouse) 105722

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功能

calcium activated cation channel activity intracellular calcium activated chloride channel activity voltage-gated ion channel activity voltage-gated chloride channel activity chloride channel activity phospholipid scramblase activity protein homodimerization activity

参与通路

dendritic cell chemotaxis activation of blood coagulation via clotting cascade transport ion transport cation transport chloride transport lipid transport blood coagulation phospholipid transport phospholipid scrambling positive regulation of bone mineralization bleb assembly regulation of ion transmembrane transport positive regulation of ion transmembrane transport purinergic nucleotide receptor signaling pathway bone mineralization involved in bone maturation sodium ion transmembrane transport negative regulation of cell volume pore complex assembly calcium activated phospholipid scrambling calcium activated phosphatidylserine scrambling calcium activated phosphatidylcholine scrambling calcium activated galactosylceramide scrambling calcium ion transmembrane transport phosphatidylserine exposure on apoptotic cell surface positive regulation of monocyte chemotaxis phosphatidylserine exposure on blood platelet cation transmembrane transport positive regulation of potassium ion export chloride transmembrane transport regulation of anion transmembrane transport positive regulation of endothelial cell apoptotic process

ANO6 Polyclonal Antibody

ANO6 Antibody (PA5-69345) in WB

产品信息

PA5-69345

免疫印迹 (WB)

种属反应

已发表种属

宿主/亚型

分类

类型

抗原

偶联物

形式

浓度

纯化类型

保存液

内含物

保存条件

运输条件

RRID

产品详细信息

靶标信息

生物信息学

性能保障

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