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Invitrogen
ANO6 Polyclonal Antibody
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ANO6 Antibody (PA5-88322) in WB
Western blot analysis of ANO6 in extracts of various cell lines. Samples were incubated with ANO6 Polyclonal antibody (Product # PA5-88322) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88322
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 750-830 of human ANO6 (NP_0010205272)
偶联物
形式
Liquid
浓度
3.92 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: IPRLVYYWSF SVPPYGDHTS YTMEGYINNT LSIFKVADFK NKSKGNPYSD LGNHTTCRYR DFRYPPGHPQ EYKHNIYYWH V; Positive Samples: A-549, Mouse liver, Rat brain; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
May act as a calcium-activated chloride channel.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F
基因别名: 2900059G15Rik; AA407480; ANO6; AW554778; BDPLT7; F730003B03Rik; SCTS; TMEM16F
UniProt ID: (Human) Q4KMQ2, (Mouse) Q6P9J9
Entrez Gene ID: (Human) 196527, (Rat) 315272, (Mouse) 105722
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated ion channel activity
voltage-gated chloride channel activity
protein binding
phospholipid scramblase activity
protein homodimerization activity
molecular_function
chloride channel activity
dendritic cell chemotaxis
activation of blood coagulation via clotting cascade
cation transport
chloride transport
blood coagulation
phospholipid transport
phospholipid scrambling
bone mineralization involved in bone maturation
regulation of anion transport
calcium activated phospholipid scrambling
calcium activated phosphatidylserine scrambling
calcium activated phosphatidylcholine scrambling
calcium activated galactosylceramide scrambling
phosphatidylserine exposure on apoptotic cell surface
phosphatidylserine exposure on blood platelet
cation transmembrane transport
positive regulation of potassium ion export
chloride transmembrane transport
positive regulation of endothelial cell apoptotic process
lipid transport
positive regulation of bone mineralization
bleb assembly
ion transmembrane transport
positive regulation of ion transmembrane transport
purinergic nucleotide receptor signaling pathway
sodium ion transmembrane transport
positive regulation of apoptotic process
negative regulation of cell volume
pore complex assembly
positive regulation of phagocytosis, engulfment
calcium ion transmembrane transport
positive regulation of monocyte chemotaxis
regulation of anion transmembrane transport
transport
ion transport
regulation of ion transmembrane transport
