Invitrogen

AP2 alpha Recombinant Rabbit Monoclonal Antibody (K01_1M83)

查看其他16个AP2 alpha抗体

问题与答案

问题与答案

问题与答案

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抗体检测数据 (1)

AP2 alpha Antibody in Western Blot (WB)

AP2 alpha Antibody in Western Blot (WB)

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AP2 alpha Antibody (MA567821) in WB

Western Blot analysis of AP2 alpha in C6 lysates using AP2 alpha Recombinant Monoclonal Antibody (Product # MA567821).

AP2 alpha Antibody in Western Blot (WB)

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AP2 alpha Antibody in Western Blot (WB) — Western Blot analysis of AP2 alpha in C6 lysates using AP2 alpha Recombinant Monoclonal Antibody (Product # MA567821).

产品信息

MA567821

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

产品规格

种属反应

Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293F

分类

Recombinant Monoclonal

类型

Antibody

克隆号

K01_1M83

抗原

A synthetic peptide of human AP2 alpha.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Protein A/G

保存液

50mM tris glycine, pH 7.4, with 0.05% BSA, 40% glycerol, 150mM NaCl

内含物

0.01% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: activating enhancer-binding protein 2 alpha; activating enhancer-binding protein 2-alpha; activator protein 2; AP-2 transcription factor; AP2-alpha; ERF-1; FLJ51761; OTTHUMP00000214240; OTTHUMP00000214243; transcription factor AP-2-alpha

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基因别名: Tcfap2a

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Entrez Gene ID: (Rat) 306862

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transcription regulatory region sequence-specific DNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription coactivator activity RNA polymerase II transcription corepressor activity transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding sequence-specific DNA binding transcription regulatory region DNA binding protein dimerization activity general transcription factor

negative regulation of transcription from RNA polymerase II promoter kidney development neural tube closure lens morphogenesis in camera-type eye outflow tract morphogenesis keratinocyte development optic vesicle morphogenesis optic cup structural organization regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter sensory perception of sound negative regulation of cell proliferation response to water deprivation embryonic pattern specification response to organic substance embryonic body morphogenesis positive regulation of gene expression retina layer formation negative regulation of transcription by competitive promoter binding neural crest cell development Schwann cell development anterior neuropore closure trigeminal nerve development oculomotor nerve formation forebrain neuron development positive regulation of cell migration positive regulation of bone mineralization response to lipopolysaccharide embryonic forelimb morphogenesis forelimb morphogenesis negative regulation of epidermal growth factor receptor signaling pathway regulation of cell proliferation inner ear morphogenesis negative regulation of apoptotic process negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process skin development regulation of cell differentiation regulation of neuron differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter sympathetic nervous system development embryonic camera-type eye morphogenesis embryonic cranial skeleton morphogenesis skeletal system morphogenesis epidermis morphogenesis palate development lens induction in camera-type eye face morphogenesis bone morphogenesis eyelid development in camera-type eye cornea development in camera-type eye positive regulation of tooth mineralization cellular response to iron ion basement membrane organization metanephric nephron development negative regulation of reactive oxygen species metabolic process