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Abnova
API5 Monoclonal Antibody (1C2)
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产品信息
H00008539-M01-100
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C2
抗原
API5 (AAH17709, 400 a.a. approximately 504 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.42 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: GEALKTEENK IKVVALKITN NINVLIKDLF HIPPSYKSTV TLSWKPVQKV EIGQKRASED TTSGSPPKKS SAGPKRDARQ IYNPPSGKYS SNLGNFNYER SLQGK
靶标信息
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AAC-11; Antiapoptosis clone 11 protein; API-5; Apoptosis inhibitor 5; Cell migration-inducing gene 8 protein; Fibroblast growth factor 2-interacting factor; fibroblast growth factor 2-interacting factor 2; FIF; FIF C1; migration-inducing protein MIG8; Protein XAGL
基因别名: AAC-11; AAC11; API5; MIG8
UniProt ID: (Human) Q9BZZ5
Entrez Gene ID: (Human) 8539
