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Invitrogen
ARHGAP6 Polyclonal Antibody
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图: 1 / 4
ARHGAP6 Antibody (PA5-104106) in ICC/IF
Immunocytochemistry analysis of ARHGAP6 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with ARHGAP6 polyclonal antibody (Product # PA5-104106) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-104106
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ARHGAP6(Accession O43182), corresponding to amino acid residues G724-G774.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total RHG6.
靶标信息
This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alternatively spliced; Rho GTPase activating protein 6; Rho GTPase-activating protein 6; Rho-type GTPase-activating protein 6; Rho-type GTPase-activating protein RhoGAPX-1; rhoGAPX-1; unnamed protein product
基因别名: AI504284; ARHGAP6; RHOGAP6; RHOGAPX-1
UniProt ID: (Mouse) O54834
Entrez Gene ID: (Human) 395, (Mouse) 11856, (Rat) 100363276
actin filament organization
signal transduction
Rho protein signal transduction
actin filament polymerization
regulation of small GTPase mediated signal transduction
negative regulation of stress fiber assembly
negative regulation of focal adhesion assembly
positive regulation of phospholipase C/protein kinase C signal transduction
positive regulation of intracellular signal transduction
activation of phospholipase C activity
positive regulation of phospholipase activity
regulation of GTPase activity
positive regulation of GTPase activity
focal adhesion assembly
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