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Invitrogen
ARIH2 Polyclonal Antibody
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产品信息
PA5-28446
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ARIH2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa, mouse muscle.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%), Chimpanzee (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: all-trans retinoic acid inducible RING finger; ARI-2; ariadne 2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; FLJ10938; FLJ33921; OTTHUMP00000210388; protein ariadne-2 homolog; Triad1 protein; UbcM4-interacting protein 48
基因别名: AI843547; ARI2; ARIH2; HT005; TRIAD1; UIP48
UniProt ID: (Human) O95376, (Mouse) Q9Z1K6
Entrez Gene ID: (Human) 10425, (Mouse) 23807
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin conjugating enzyme binding
ubiquitin protein ligase activity
nucleic acid binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
protein polyubiquitination
multicellular organism development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
developmental cell growth
protein K63-linked ubiquitination
protein K48-linked ubiquitination
hematopoietic stem cell proliferation
positive regulation of protein targeting to mitochondrion
ubiquitin-dependent protein catabolic process
