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Abnova
ARL6IP6 Polyclonal Antibody, MaxPab™
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产品信息
H00151188-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ARL6IP6 (NP_689735.1, 1 a.a. approximately 226 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSFAESGWRS ALRRRGPGTP GPVARPSYSS FTQGDSWGEG EVDEEEGCDQ VARDLRAEFS AGAWSEPRKR SVLPPDGNGS PVLPDKRNGI FPAAAGSRAQ PRRWPVQVLS ILCSLLFAIL LAFLLAIAYL IVKELHAENL KNEDDVDTGL LGFWTLLIIS LTAGFSCCSF SWTVTYFDSF EPGMFPPTPL SPARFKKLTG HSFHMGYSMA ILNGIVAALT VAWCLM
靶标信息
The ARL6IP6 gene has been identified as a novel candidate gene associated with a syndromic form of Cutis Marmorata Telangiectatica Congenita (CMTC), suggesting that ischemic stroke or transient ischemic attacks (TIA) might represent the mild end of the phenotypic spectrum, with autosomal recessive CMTC as the severe manifestation. The ARL6IP6 influences the susceptibility to these conditions, highlighting its importance in vascular and dermatological syndromes. Mutations in ARL6IP6 can lead to a range of phenotypic outcomes, from mild ischemic events to serious congenital skin disorders, emphasizing the need for deeper genetic and phenotypic exploration to understand its role in human pathology. Moreover, the gene is potentially involved in intracellular trafficking processes that are crucial for proper cellular function, which can be impacted by genetic variations, leading to clinical manifestations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor GTPase 6 interacting protein 6; ADP-ribosylation factor like GTPase 6 interacting protein 6; ADP-ribosylation factor-like 6 interacting protein 6; ADP-ribosylation factor-like protein 6-interacting protein 6; ADP-ribosylation-like factor 6 interacting protein 6; ARL-6-interacting protein 6; Phosphonoformate immuno-associated protein 1; regulated by phosphonoformate
基因别名: AIP-6; AIP6; ARL6IP6; PFAAP1
UniProt ID: (Human) Q8N6S5
Entrez Gene ID: (Human) 151188
