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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGGPRGAGWV AAGLLLGAGA CYCIYRLTRG RRRGDRELGI RSSKSAEDLT DGSYDDVLNA EQLQKLLYLL ESTEDPVIIE RALITLGNNA AFSVNQAIIR ELGGIPIVAN KINHSNQSIK EKALNALNNL SVNVENQIKI KIYISQVCED VFSGSLNSAV QLAGLTLLTN MTVTNDHQHM LHSYITDLFQ VLLTGNGNTK VQVLKLLLNL SENPAMTEGL LRAQVDSSFL SLYDSHVAKE ILLRVLTLFQ NIKNCLKIEG HLAVQPTFTE GSLFFLLHGE ECAQKIRALV DHHDAEVKEK VVTIIPKI
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: specific splicing variant involved in hepatocarcinogenesis; splicing variant involved in hepatocarcinogenesis protein; unnamed protein product
基因别名: PNAS-112; PNAS112; PSEC0198; SVH
UniProt ID: (Human) Q8N2F6
Entrez Gene ID: (Human) 83787