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Invitrogen
ARPP19 Polyclonal Antibody
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产品信息
PA5-63357
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MSAEVPEAAS AEEQKEMEDK VTSPEKAEEA K
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARPP-19; cAMP regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein 19kDa; cAMP-regulated phosphoprotein, 19kDa; cyclic AMP phosphoprotein, 19 kD
基因别名: ARPP-16; ARPP-19; ARPP16; ARPP19; ENSAL
UniProt ID: (Human) P56211
Entrez Gene ID: (Human) 10776
