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Invitrogen
ARPP19 Polyclonal Antibody
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产品信息
PA5-70811
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the N-terminal of mouse ARPP19
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARPP-19; cAMP-regulated phosphoprotein 19; cAMP-regulated phosphoprotein ARPP-19; cyclic AMP phosphoprotein, 19 kDa; cyclic AMP phosphoprotein, 19kD
基因别名: 19kDa; 2700024H10Rik; ARPP-19; Arpp12; Arpp19; AW559096
UniProt ID: (Mouse) P56212
Entrez Gene ID: (Mouse) 59046
