Invitrogen

ARRDC1 Polyclonal Antibody

Name: ARRDC1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-50913

查看其他3个ARRDC1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

图: 1 / 2

ARRDC1 Antibody (PA5-50913) in WB

Western Blot analysis of ARRDC1 was performed using Jurkat cells. The membrane was probed with ARRDC1 Polyclonal Antibody (Product # PA5-50913).

Product Image Gallery

Immunogen image

Immunogen Image ARRDC1 Polyclonal Antibody

产品信息

PA5-50913

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthesized peptide derived from the Internal region of human Arrdc1 (aa 167-216).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 0.5% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2636361

产品详细信息

ARRDC1 Polyclonal Antibody detects endogenous levels of ARRDC1 protein.

靶标信息

Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating in the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940). [UniProt]

仅用于科研。不用于诊断过程。未经明确授权不得转售。