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Invitrogen
ARRDC3 Polyclonal Antibody
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FIGURE: 1 / 1
ARRDC3 Antibody (PA5-98679) in WB
Western Blot analysis of ARRDC3 using a ARRDC3 Polyclonal antibody (Product # PA5-98679) at a concentration of 4 µg/mL. Positive WB detected in: MCF-7 whole cell lysate, Mouse skeletal muscle tissue. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 47 kDa.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-98679
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Arrestin domain-containing protein 3 protein (1-270AA)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis of activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arrestin domain-containing protein 3
Gene Aliases: AI450344; Arrdc3; Kiaa1376; mKIAA1376
UniProt ID: (Mouse) Q7TPQ9
Entrez Gene ID: (Mouse) 105171
temperature homeostasis
negative regulation of heat generation
skin development
negative regulation of multicellular organismal metabolic process
positive regulation of ubiquitin-protein transferase activity
fat pad development
positive regulation of adrenergic receptor signaling pathway
negative regulation of locomotion involved in locomotory behavior
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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