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Invitrogen
ARSA Recombinant Mouse Monoclonal Antibody (K29073_19C6)
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ARSA Antibody (MA564493) in WB
Western blot analysis of ARSA in HeLa lysate (15 μg). Samples were incubated with ARSA recombinant monoclonal (Product # MA564493) using a dilution of 1 µg/mL followed by peroxidase conjugated goat anti-mouse IgG. Sample was run on 6-18% SDS-PAGE under reducing conditions and blotted onto nitrocellulose membrane. ARSA band was visualized using ECL Western Blotting Substrate.
产品信息
MA564493
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
K29073_19C6
抗原
Recombinant human ARSA (aa 241-480).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 50% glycerol, 0.5% BSA
内含物
0.09% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RSGRGPFGDS LMELDAAVGT LMTAIGDLGL LEETLVIFTA DNGPETMRMS RGGCSGLLRC GKGTTYEGGV REPALAFWPG HIAPGVTHEL ASSLDLLPTL AALAGAPLPN VTLDGFDLSP LLLGTGKSPR QSLFFYPSYP DEVRGVFAVR TGKYKAHFFT QGSAHSDTTA DPACHASSSL TAHEPPLLYD LSKDPGENYN LLGGVAGATP EVLQALKQLQ LLKAQLDAAV TFGPSQVARG
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 39%, Pig - 91%, Cynomolgus monkey - 97%.
靶标信息
The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy, a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARSA-I; ARSA1; Arylsulfatase A; ASA; ASNA-I; ATPase ASNA1; Cerebroside-sulfatase; EC 3.1.6.8; GET3; hASNA-I; TRC40
基因别名: ARSA; MLD
UniProt ID: (Human) P15289
Entrez Gene ID: (Human) 410
