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Invitrogen
ARTS Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-19389
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (RNKLTRESGTD) corresponding to the internal amino acids of 38231 (aa 425-435).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine and canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
靶标信息
Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; bradeion beta; brain protein H5; CE5B3 beta; cell division control-related protein 2; cerebral protein 7; peanut-like protein 2; PNUTL2; SEPT4 isoform 2; SEPT4_i2; septin-M; similar to mouse brain protein h5; uncharacterized protein C17orf47; unnamed protein product
基因别名: ARTS; BRADEION; C17orf47; CE5B3; H5; hCDCREL-2; hucep-7; MART; PNUTL2; SEP4; SEPT4; Septin-4; SPGF99
UniProt ID: (Human) O43236
Entrez Gene ID: (Human) 5414
neuron migration
apoptotic process
protein localization
regulation of exocytosis
sperm motility
positive regulation of protein ubiquitination
regulation of apoptotic process
positive regulation of apoptotic process
spermatid differentiation
hematopoietic stem cell homeostasis
cytoskeleton-dependent cytokinesis
positive regulation of intrinsic apoptotic signaling pathway
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