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Invitrogen
ARX Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-113264
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Homeobox protein ARX protein (381-460AA)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
3.64 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Arx contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. It is a member of the group-II aristaless-related protein family whose members are expressed primarily in the central and/or peripheral nervous system. This protein is thought to be involved in CNS development. Mutations in the Arx gene cause X-linked mental retardation and epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aristaless-related homeobox, X-linked; ARX; transcription factor; homeobox; cancer/testis antigen 121
基因别名: Arx1; CT121; EIEE1; ISSX; MRX29; MRX32; MRX33; MRX36; MRX38; MRX43; MRX54; MRX76; MRX87; MRXS1; PRTS; RGD1562672
UniProt ID: (Human) Q96QS3, (Mouse) O35085, (Rat) A6YP92
Entrez Gene ID: (Human) 170302, (Mouse) 11878, (Rat) 317268
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
protein binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
neuron migration
pancreatic A cell differentiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
axon guidance
positive regulation of gene expression
globus pallidus development
olfactory bulb development
cerebral cortex tangential migration
embryonic olfactory bulb interneuron precursor migration
cell proliferation in forebrain
cerebral cortex GABAergic interneuron migration
forebrain development
enteroendocrine cell differentiation
regulation of cell proliferation
lipid digestion
positive regulation of transcription from RNA polymerase II promoter
positive regulation of organ growth
neuron development
epithelial cell fate commitment
intestinal type G enteroendocrine cell differentiation
intestinal type I enteroendocrine cell differentiation
intestinal type L enteroendocrine cell differentiation
intestinal type N enteroendocrine cell differentiation
intestinal type D enteroendocrine cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
