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Invitrogen
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Immunogen sequence: HHHCRRNPEL QEELQIQAAV AAGDVHTVRK MLEQGYSPNG RDANGWTLLH FSAARGKERC VRVFLEHGAD PTVKDLIGGF TALHYAAMHG RARIARLMLE SEYRSDIINA KSNDGWTPLH VAAHYGRDSF VRLLLEFKAE VDPLSDK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ankyrin repeat and SOCS box protein 7; ankyrin repeat and SOCS box-containing 7; ASB-7
基因别名: ASB7
UniProt ID: (Human) Q9H672
Entrez Gene ID: (Human) 140460