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Abnova
ASCC1 Polyclonal Antibody, MaxPab™
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产品信息
H00051008-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ASCC1 (NP_057031.2, 1 a.a. approximately 357 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEVLRPQLIR IDGRNYRKNP VQEQTYQHEE DEEDFYQGSM ECADEPCDAY EVEQTPQGFR STLRAPSLLY KHIVGKRGDT RKKIEMETKT SISIPKPGQD GEIVITGQHR NGVISARTRI DVLLDTFRRK QPFTHFLAFF LNEVEVQEGF LRFQEEVLAK CSMDHGVDSS IFQNPKKLHL TIGMLVLLSE EEIQQTCEML QQCKEEFIND ISGGKPLEVE MAGIEYMNDD PGMVDVLYAK VHMKDGSNRL QELVDRVLER FQASGLIVKE WNSVKLHATV MNTLFRKDPN AEGRYNLYTA EGKYIFKERE SFDGRNILKL FENFYFGSLK LNSIHISQRF TVDSFGNYAS CGQIDFS
靶标信息
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activating signal cointegrator 1 complex subunit 1; ASC-1 complex subunit P50; Trip4 complex subunit p50
基因别名: ASC1p50; ASCC1; CGI-18; p50; SMABF2
UniProt ID: (Human) Q8N9N2
Entrez Gene ID: (Human) 51008
