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Invitrogen
ASGR2 Polyclonal Antibody
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ASGR2 Antibody (PA5-89547) in WB
Western blot analysis of ASGR2 in extracts of various cell lines. Samples were incubated with ASGR2 Polyclonal antibody (Product # PA5-89547) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-89547
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 131-287 of human ASGR2 (NP_5504351)
偶联物
形式
Liquid
浓度
2.84 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VDLRFVACQM ELLHSNGSQR TCCPVNWVEH QGSCYWFSHS GKAWAEAEKY CQLENAHLVV INSWEEQKFI VQHTNPFNTW IGLTDSDGSW KWVDGTDYRH NYKNWAVTQP DNWHGHELGG SEDCVEVQPD GRWNDDFCLQ VYRWVCEKRR NATGEVA; Positive Samples: Mouse liver, Rat liver; Cellular Location: Membrane, Single-pass type II membrane protein
靶标信息
ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ANCO-2; ANCO1; ASGP-R 2; ASGPR 2; Asialoglycoprotein receptor 2; GAC-1; Hepatic lectin 2; hepatic lectin 2 RHL2; hepatic lectin 2, RHL2; Hepatic lectin R2/3; HL-2; mHL-2; Nbla00144; RHL-2
基因别名: ASGPR2; Asgr; Asgr-2; Asgr2
UniProt ID: (Mouse) P24721, (Rat) Q5M8C9
Entrez Gene ID: (Mouse) 11890, (Rat) 29403
