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Alomone Labs, LTD
ASIC2a Polyclonal Antibody, Atto™ 594
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ASIC2a Antibody (ASC-012-AR-50UL) in IHC (F)
Expression of ASIC2a in rat cerebellum and spinal cord - Immunohistochemical staining of perfusion-fixed frozen rat brain and spinal cord sections using Anti-ASIC2a-ATTO Fluor-594 Antibody (#ASC-012-AR), (1:60). A. Staining in rat cerebellum sections reveals ASIC2a expression (red) in the molecular layer (MOL) of the cerebellar cortex. B. Staining in rat spinal cord sections shows labeling (red) of neuronal... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ASC-012-AR-50UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DLKESPSEGSLQPSSIQC, corresponding to amino acid residues 2-18 of human ASIC2a, Intracellular, N-terminus
偶联物
Atto™ 594
Atto™ 594
Atto™ 594
激发/发射光谱
602/622 nm
形式
Lyophilized
浓度
1 mg/mL
规格
50 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acid sensing (proton gated) ion channel 2; acid-sensing (proton-gated) ion channel 2; acid-sensing proton-gated ion channel 2 short variant MDEG2; ACNN1; amiloride-sensitive brain sodium channel; amiloride-sensitive brain sodium channel 2; amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Asic2 short variant MDEG2; BNaC1 alpha; BNC1; brain Na+ channel-1; brain sodium channel 1; degenerin; mammalian degenerin homolog; neuronal amiloride-sensitive cation channel 1; unnamed protein product
基因别名: ACCN; ACCN1; ACIC2; ASIC2a; BNaC1; BNaC1a; BNC1; BNC1k; hBNaC1; MDEG; MDEG1; MDEG2
UniProt ID: (Human) Q16515, (Rat) Q62962, (Mouse) Q925H0
Entrez Gene ID: (Human) 40, (Rat) 25364, (Mouse) 11418
regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
cation transport
sodium ion transport
phototransduction
sensory perception of sound
response to mechanical stimulus
response to acidic pH
regulation of vasoconstriction
ion transmembrane transport
regulation of ion transmembrane transport
protein localization to synapse
sodium ion transmembrane transport
regulation of membrane potential
negative regulation of apoptotic process
sensory perception of sour taste
detection of mechanical stimulus involved in sensory perception
positive regulation of synapse assembly
cellular response to xenobiotic stimulus
cellular response to acidic pH
regulation of postsynapse assembly
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