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A 1:1,000 dilution of PA5-77776 was sufficient for detection of ATG9B in 15 µg of Human HeLa Cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.|Detects approximately 100 kDa.
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: APG9-like 2; ATG9; ATG9 autophagy related 9 homolog B; autophagy 9-like 2 protein; Autophagy-related protein 9B; endothelial nitric oxide synthase antisense; nitric oxide synthase 3 antisense; Nitric oxide synthase 3-overlapping antisense gene protein; Protein sONE
基因别名: Apg912; APG9L2; Apgdc2; ATG9B; eONE; Gm574; NOS3AS; SONE
UniProt ID: (Human) Q674R7, (Mouse) Q6EBV9
Entrez Gene ID: (Human) 285973, (Mouse) 213948