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Invitrogen
ATIC Monoclonal Antibody (F38 P7 H9)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA1-086
应用
建议稀释比
已发表文章
产品规格
种属反应
Fruit fly,
Human,
Mouse,
Rat,
Xenopus
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
F38 P7 H9
抗原
Synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-086 detects the ATIC in human, rat, Xenopus, Drosophila, and mouse cells.
MA1-086 has been successfully used in Western blot and immunohistochemistry (parrafin) procedures. By Western blot, this antibody detects a ~64.6 kDa protein.
The MA1-086 immunogen is a synthetic peptide, conjugated to Ovalbumin, corresponding to residues A(583) H T N L R L F H H(592) of human ATIC..
靶标信息
ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase/inosine monophosphate cyclohydrolase; bifunctional purine biosynthesis protein PURH; bifunctional purine biosynthesis protein PURH-like; epididymis secretory sperm binding protein Li 70p; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; unnamed protein product
基因别名: 2610509C24Rik; AICAR; AICARFT; atic; HEL-S-70p; IMPCHASE; PURH; XELAEV_18044849mg
UniProt ID: (Human) P31939, (Mouse) Q9CWJ9, (Rat) O35567
Entrez Gene ID: (Human) 471, (Mouse) 108147, (Rat) 81643, (Xenopus) 735175
brainstem development
nucleobase-containing compound metabolic process
purine nucleotide biosynthetic process
GMP biosynthetic process
'de novo' IMP biosynthetic process
cerebellum development
cerebral cortex development
organ regeneration
'de novo' AMP biosynthetic process
dihydrofolate metabolic process
tetrahydrofolate biosynthetic process
'de novo' XMP biosynthetic process
cellular response to interleukin-7
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
