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Abnova
ATMIN Polyclonal Antibody, MaxPab™
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产品信息
H00023300-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ATMIN (AAH02701.1, 1 a.a. approximately 667 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKMHAEKKHK CSKCSNSYGT EWDLKRHAED CGKTFRCTCG CPYASRTALQ SHIYRTGHEI PAEHRDPPSK KRKMENCAQN QKLSNKTIES LNNQPIPRPD TQELEASEIK LEPSFEDSCG SNTDKQTLTT PPRYPQKLLL PKPKVALVKL PVMQFSVMPV FVPTADSSAQ PVVLGVDQGS ATGAVHLMPL SVGTLILGLD SEACSLKESL PLFKIANPIA GEPISTGVQV NFGKSPSNPL QELGNTCQKN SISSINVQTD LSYASQNFIP SAQWATADSS VSSCSQTDLS FDSQVSLPIS VHTQTFLPSS KVTSSIAAQT DAFMDTCFQS GGVSRETQTS GIESPTDDHV QMDQAGMCGD IFESVHSSYN VATGNIISNS LVAETVTHSL LPQNEPKTLN QDIEKSAPII NFSAQNSMLP SQNMTDNQTQ TIDLLSDLEN ILSSNLPAQT LDHRSLLSDT NPGPDTQLPS GPAQNPGIDF DIEEFFSASN IQTQTEESEL STMTTEPVLE SLDIETQTDF LLADTSAQSY GCRGNSNFLG LEMFDTQTQT DLNFFLDSSP HLPLGSILKH SSFSVSTDSS DTETQTEGVS TAKNIPALES KVQLNSTETQ TMSSGFETLG SLFFTSNETQ TAMDDFLLAD LAWNTMESQF SSVETQTSAE PHTVSNF
靶标信息
The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51. ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects. It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASCIZ; ATM INteracting protein; ATM interactor; ATM/ATR-substrate CHEK2-interacting zinc finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; Zinc finger protein 822
基因别名: ASCIZ; ATMIN; KIAA0431; ZNF822
UniProt ID: (Human) O43313
Entrez Gene ID: (Human) 23300
