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Invitrogen
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Immunogen sequence: LCLLCSGSSS PATAPHPLKM FACSKFVSTP SLVKSTSQLL SRPLSAVVLK RPEILTDESL SSLAVSCPLT SLVSSRSFQ
Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 58%.
ATP5MC2 encodes the enzyme ATP5MC2, which is a subunit of the mitochondrial ATP synthase complex (Complex V). The ATP synthase complex is pivotal in the process of oxidative phosphorylation and ADP to ATP conversion, which is essential for energy production in the cell. The ATP5MC2 gene is located on chromosome 12. This subunit helps in forming the membrane channel of the F0 portion of the ATP synthase complex, facilitating proton translocation across the mitochondrial membrane. Mutations or dysfunction in this gene can lead to mitochondrial deficiencies and energy production disorders, which may have implications in various metabolic and neurodegenerative conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP synthase c subunit; ATP synthase F(0) complex subunit C2, mitochondrial; ATP synthase lipid-binding protein; ATP synthase lipid-binding protein, mitochondrial; ATP synthase membrane subunit c locus 2; ATP synthase proteolipid P2; ATP synthase proton-transporting mitochondrial F(0) complex subunit C2; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9); ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9); ATPase protein 9; ATPase subunit 9; ATPase subunit C; dicyclohexylcarbodiimide (DCCD)-reactive proteolipid subunit; unnamed protein product
基因别名: ATP5A; ATP5G2; ATP5MC2; PSEC0033
UniProt ID: (Human) Q06055
Entrez Gene ID: (Human) 517