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Invitrogen
ATP6V1G2 Polyclonal Antibody
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ATP6V1G2 Antibody (PA5-116928) in IHC (P)
Immunohistochemistry analysis of ATP6V1G2 in paraffin-embedded mouse spinal cord. Samples were incubated with ATP6V1G2 Polyclonal antibody (Product # PA5-116928) using a dilution of 1:50 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-116928
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 40-100 of human ATP6V1G2 (NP_5697301)
偶联物
形式
Liquid
浓度
0.62 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: SH-SY5Y, Mouse brain, Rat brain, Mouse eye
Immunogen sequence: AQMEVEQYRR EREHEFQSKQ QAAMGSQGNL SAEVEQATRR QVQGMQSSQQ RNRERVLAQL L
靶标信息
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. This gene had previous gene symbols of ATP6G and ATP6G2. Alternatively spliced transcript variants encoding different isoforms have been described. Read-through transcription also exists between this gene and the downstream DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (DDX39B) gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase, H+ transporting, lysosomal (vacuolar proton pump); ATPase, H+ transporting, lysosomal 13kD, V1 subunit G; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2; ATPase, H+ transporting, V1 subunit G; H(+)-transporting two-sector ATPase, subunit G2; lysosomal 13kDa; V-ATPase 13 kDa subunit 2; V-ATPase subunit G 2; V-type proton ATPase subunit G 2; vacuolar ATP synthase subunit G 2; vacuolar ATPase NG38; vacuolar proton pump G subunit 2; Vacuolar proton pump subunit G 2
基因别名: 1500002D01Rik; ATP6G; ATP6G2; ATP6V1G2; NG38; VAG2; VMA10
UniProt ID: (Human) O95670, (Mouse) Q9WTT4
Entrez Gene ID: (Human) 534, (Rat) 368044, (Mouse) 66237
